Cyclobenzaprine: What Is It? Side Effects & Interactions Cleveland Clinic
This is more likely to happen in the few hours after you take it. A long-acting formulation of cyclobenzaprine has been introduced and is believed by some clinicians to have a lower side effect profile than the immediate-release formulation of this drug. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not stand or sit up quickly, especially if you are an older patient. Alcohol may interfere with the effect of this medication.
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The generic form was first approved in 1977 and is sold in both immediate and extended release versions. Older adults may be more sensitive to the side effects of this drug, especially drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can increase the risk of falling. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Before taking cyclobenzaprine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
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For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
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It is ineffective in muscle spasm due to central nervous system disease. Other potential effects of overdosage include any of the symptoms listed under ADVERSE REACTIONS. It is not known whether this drug is excreted in human milk.
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After you eat the mixture, take a drink, and swish and swallow to make sure that you have received all the medication. Do not use the extended-release capsules if you have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within 14 days of each other. If you cannot swallow the capsule whole, you may open the capsule and sprinkle the contents over one tablespoon of applesauce.
- It works by acting in the brain and nervous system to allow the muscles to relax.
- Maximum daily dose for either form is 30 mg over the course of 24 hours.
- This can help keep levels of this drug from building up too much in your body.
- Do not start, stop, or change the dosage of any medicines without your doctor’s approval.
- Cyclobenzaprine caused slight to moderate increase in heart rate in animals.
- If you are prescribed cyclobenzaprine, follow your healthcare provider’s directions for how to take it.
This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 3 Sep 2023), Cerner Multum™ (updated 28 Aug 2023), ASHP (updated 10 Aug 2023) and others. Yes, cyclobenzaprine can make you very sleepy and this side effect may get worse with higher doses. Drowsiness is the most commonly reported side effect in studies, occurring in up to 38% (38 out of 100) of people. Avoid or limit the use of alcohol or other sedating medicines while being treated with cyclobenzaprine. Also avoid driving, operating machinery, or other hazardous activities until you know how cyclobenzaprine affects you.
The kidneys of older adults may not work as well as they used to. As a result, more of a drug stays in your body for longer. Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.
If consciousness is impaired, the airway should be secured prior to lavage and emesis is contraindicated. Using Flexeril with other drugs that make you can i take tramadol with flexeril drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
What should I tell my care team before I take this medication?
Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk with your doctor or pharmacist. If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk with your doctor or pharmacist. Elderly patients seem to tolerate cyclobenzaprine less and may develop hallucinations as well as significant anticholinergic side effects, such as sedation.